Osteogenesis Imperfecta (OI) - Beagle Startseite ACHM develops due to genetic

ACHM develops due to genetic defects which results in complete loss of cone function and activity of ion channel which is a key mediator in signal transduction in retinal receptors

that affect foetal development

Affected dogs experience unpredictable seizures with increased aggression

aw/at or aw/a alleles

The condition is progressive

Osteogenesis Imperfecta (OI) - Beagle Startseite ACHM develops due to geneticOsteogenesis imperfecta is an autosomal dominant disease caused by a mutation in the COLA2 gene, which encodes collagen. Mutations altering the sequence can lead to disruptions of the collagen structure, which can lead to abnormally brittle bones that fracture very easily. The disease can be found in several dog breeds. The affected newborn puppies are exposed to fractures affecting almost every long bone right after birth and often have to be