Alexander Krankheit Hundebesitzer-Featured along with paroxysmal neurological episodes

along with paroxysmal neurological episodes consisting of head tremors and involuntary movements of one of the front limbs

Hair length is one of the most important morphological features of dogs

Cerebellum (a part of brain) and Purkinje cells play essential role in motor control as well as they are responsible for coordinating movement and balance

The dog has short hair

DCM is associated with 4 different risk variants

Alexander Krankheit Hundebesitzer-Featured along with paroxysmal neurological episodesAlexander disease is a progressive fatal neurodegenerative hereditary disorder, caused by astrocyte dysfunction. Astrocytes are specialized cells in the brain and spinal cord, which contain a specific protein called glial fibrillary acidic protein (GFAP). Mutation in GFAP gene is the most common cause of the disease. The age of affected dogs is usually less than 12 months. Clinical signs begin as incoordination, a head tilt, knuckling on limbs, issues