Neuronale Zeroidlipofuszinose (NCL-8) - Australian Shepherd-Typ evg-analysen It is caused by axonal

It is caused by axonal swelling in the cerebellum and abnormalities in the brain stem

MM = double merle

basierend auf der Vererbung der Risikovarianten DCM3 und DCM4 (für ein besseres Verständnis siehe die Tabelle unten)

Die Krankheit tritt bei mittelalten Labrador-Retrievern auf

aber die Produktion von Eumelanin in der Nase

Neuronale Zeroidlipofuszinose (NCL-8) - Australian Shepherd-Typ evg-analysen It is caused by axonalNeuronal ceroid lipofuscinosis (NCLs) are a group of hereditary diseases, characterized by progressive neuronal degeneration and the accumulation of autofluorescent cytoplasmic inclusions in the brain, retina, and other tissues. Clinical symptoms and progress of the disease include increased rates of irritability, with the possibility of outbursts of aggression, hallucinations, hyperactivity and seizures. Most animals lose their ability to coordinate