E-Lokus DogCheck There is currently no specific

There is currently no specific treatment available for this disease

Chondrodysplasia (CDPA) is defined as an inherited condition characterized by abnormal growth at the ends of bones

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Hh = harlequin

In Australian Shepherds the disease was identified between 4 and 19 months of age

E-Lokus DogCheck There is currently no specificMelanocortin 1 receptor (MC1R) on E Locus is responsible for regulation of pigment production in melanocytes. Mutation inMC1R gene results in non functional receptor and switches pigment production to pheomelanin. Because production of eumelanin is disabled, effect of other loci is not possible. Mutation is recessive therefore, two such alleles are necessary for yellow red (pheomelanin) coat colour expression. Different dog breeds with genotype e e