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Trapped Neutrophil Syndrome (TNS) Züchter an additional gene sequence has

SKU: 16058348681
4.7

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Description

an additional gene sequence has been inserted within the affected gene PMEL17

DLA Haplotypes: Analysis of immune-relevant gene variants – significant for minimizing autoimmune-related risks

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The affected dogs usually have to be euthanised at around 20 months of age due to progressive neurological decline

Hunde unterscheiden sich erheblich in ihren morphologischen Eigenschaften

Trapped Neutrophil Syndrome (TNS) Züchter an additional gene sequence hasTrapped neutrophil syndrome (TNS) is an autosomal recessive inherited neutropenia in the Border Collie breed. The disease, originally detected in Border Collies in Australia and New Zealand in the 1990's, is characterized by a marked reduction in numbers of neutrophils in peripheral blood and a hyperplasia of myeloid cells in bone marrow. Due to the severe neutropenia, affected dogs are consistently subject to life threatening infections, resulting in

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